{"id":6735,"date":"2025-11-21T11:08:50","date_gmt":"2025-11-21T11:08:50","guid":{"rendered":"https:\/\/chemgramx.com\/?post_type=product&#038;p=6735"},"modified":"2025-11-21T11:09:14","modified_gmt":"2025-11-21T11:09:14","slug":"order-25i-nbmd-online","status":"publish","type":"product","link":"https:\/\/chemgramx.com\/cs\/product\/25i-nbmd-online-bestellen\/","title":{"rendered":"Objednat 25I-NBMD online"},"content":{"rendered":"<p>T\u0159\u00edda <span class=\"math-inline\" data-math=\"mathbf{N}\">N<\/span>&#8211;<b>Benzylfenetylaminov\u00e9 deriv\u00e1ty<\/b> m\u00e1 velk\u00fd v\u00fdznam pro studium molekul\u00e1rn\u00ed farmakologie. <b>25I-NBMD<\/b> je syntetick\u00e1 v\u00fdzkumn\u00e1 chemick\u00e1 l\u00e1tka z <b>Rodina NBOMe<\/b>kter\u00fd <b>v\u00fdhradn\u011b<\/b> je ur\u010den pro v\u011bdeck\u00fd v\u00fdzkum a farmakologick\u00e9 anal\u00fdzy v p\u0159\u00edsn\u011b kontrolovan\u00e9m laboratorn\u00edm prost\u0159ed\u00ed. D\u00edky sv\u00e9 <b>vysok\u00e1 afinita<\/b> Vazbou na centr\u00e1ln\u00ed neurotransmiterov\u00e9 receptory slou\u017e\u00ed 25I-NBMD jako z\u00e1sadn\u00ed modelov\u00fd syst\u00e9m v oblasti <b>V\u00fdzkum receptor\u016f<\/b>.<\/p>\n<p>L\u00e1tka je <b>v\u00fdhradn\u011b pro analytick\u00e9 a v\u011bdeck\u00e9 studie<\/b> nab\u00edzen\u00e9. Zd\u016fraz\u0148ujeme, \u017ee 25I-NBMD je vzhledem ke sv\u00e9 mimo\u0159\u00e1dn\u00e9 \u00fa\u010dinnosti a farmakologick\u00e9 aktivit\u011b. <b>nejp\u0159\u00edsn\u011bj\u0161\u00ed bezpe\u010dnostn\u00ed a pr\u00e1vn\u00ed protokoly<\/b> podl\u00e9h\u00e1 a <b>nejsou ur\u010deny k lidsk\u00e9 spot\u0159eb\u011b<\/b> je.<\/p>\n<h2>Chemick\u00e1 struktura, farmakologie a vlastnosti<\/h2>\n<p>Kl\u00ed\u010dem k jeho v\u011bdeck\u00e9mu v\u00fdznamu je molekul\u00e1rn\u00ed konfigurace 25I-NBMD a z n\u00ed vypl\u00fdvaj\u00edc\u00ed vysok\u00e1 afinita k receptor\u016fm.<\/p>\n<h3>Co je 25I-NBMD?<\/h3>\n<p>Chemicky je <b>25I-NBMD<\/b> zn\u00e1m\u00fd jako <b>2-(4-jodo-2,5-dimethoxyfenyl)-N-(2-methoxybenzyl)ethanamin<\/b>.<\/p>\n<ul>\n<li><b>T\u0159\u00edda struktury:<\/b> Je jedn\u00edm z <span class=\"math-inline\" data-math=\"mathbf{N}\">N<\/span>&#8211;<b>Benzylfenetylaminov\u00e9 deriv\u00e1ty<\/b>.<\/li>\n<li><b>Substituce j\u00f3du:<\/b> Na str\u00e1nk\u00e1ch <span class=\"math-inline\" data-math=\"mathbf{4}\">4<\/span>&#8211;<b>Skupina Iodo<\/b> a <span class=\"math-inline\" data-math=\"mathbf{2,5}\">{2,5}<\/span>&#8211;<b>Dimethoxy skupiny<\/b> na fenylov\u00e9m kruhu jsou charakteristick\u00e9 pro tuto t\u0159\u00eddu \u00fa\u010dinn\u00fdch l\u00e1tek.<\/li>\n<li><b>N-benzylov\u00e1 modifikace:<\/b> Na str\u00e1nk\u00e1ch <b><span class=\"math-inline\" data-math=\"mathbf{N}\">N<\/span>-(2-methoxybenzyl) skupina<\/b> je \u00fast\u0159edn\u00ed modifikac\u00ed, kter\u00e1 <b>P\u0159\u00edbuznost s p\u0159\u00edlohou<\/b> na <span class=\"math-inline\" data-math=\"mathbf{5-HT_{2A}}\">5-HT-2A <\/span><b>Receptor<\/b> v\u00fdrazn\u011b zv\u00fd\u0161il.<\/li>\n<\/ul>\n<p>25I-NBMD je <b>agonista s vysokou afinitou<\/b> o <span class=\"math-inline\" data-math=\"mathbf{5-HT_{2A}}\">5-HT_2A<\/span><b>-receptor<\/b>. V\u00fdzkum vyu\u017e\u00edv\u00e1 t\u00e9to mimo\u0159\u00e1dn\u011b siln\u00e9 vazebn\u00e9 vlastnosti k p\u0159esn\u00e9mu mapov\u00e1n\u00ed hustoty, distribuce a funk\u010dn\u00ed aktivity t\u011bchto receptor\u016f na laboratorn\u00edch modelech. Zpr\u00e1vy z v\u00fdzkumn\u00fdch projekt\u016f nazna\u010duj\u00ed <b>Intenzivn\u00ed \u00fa\u010dinek<\/b> na smyslov\u00e9 syst\u00e9my, co\u017e zd\u016fraz\u0148uje v\u00fdznam tohoto spojen\u00ed pro studium fenom\u00e9n\u016f v\u011bdom\u00ed.<\/p>\n<h3>V\u011bdeck\u00e9 v\u00fdzkumn\u00e9 aplikace<\/h3>\n<p>Jako vysoce specifick\u00fd ligand pro serotonergn\u00ed receptory je 25I-NBMD cenn\u00fdm n\u00e1strojem v neurofarmakologii:<\/p>\n<ul>\n<li><b>V\u00fdzkum serotonergn\u00edch receptor\u016f:<\/b> Hlavn\u00ed oblast\u00ed pou\u017eit\u00ed je p\u0159esn\u00e9 zkoum\u00e1n\u00ed <b>Funkce a rozd\u011blen\u00ed<\/b> o<span class=\"math-inline\" data-math=\"mathbf{5-HT_{2A}}\">5-HT_2A<\/span>-v bun\u011b\u010dn\u00fdch kultur\u00e1ch nebo preklinick\u00fdch modelech.<\/li>\n<li><b>Analytick\u00e1 standardizace:<\/b> 25I-NBMD slou\u017e\u00ed jako <b>analytick\u00fd referen\u010dn\u00ed standard<\/b> pro <b>LC-MS\/MS<\/b> a <b>GC-MS<\/b> pro v\u00fdvoj a validaci <b>forenzn\u00ed detek\u010dn\u00ed metody<\/b> pro nov\u00e9 psychoaktivn\u00ed l\u00e1tky.<\/li>\n<li><b>Studie o zm\u011bn\u011bn\u00fdch stavech v\u011bdom\u00ed:<\/b> Experiment\u00e1ln\u00ed anal\u00fdzy v oboru psychofarmakologie zkoumaj\u00ed molekul\u00e1rn\u00ed mechanismy, kter\u00e9 jsou z\u00e1kladem <b>Zp\u016fsob \u00fa\u010dinku psychedelick\u00fdch l\u00e1tek<\/b> jsou z\u00e1kladem.<\/li>\n<li><b>Molekul\u00e1rn\u00ed farmakologie:<\/b> Ur\u010den\u00ed<span class=\"math-inline\" data-math=\"mathbf{K_i}\">K_i<\/span>-(vazebn\u00e9 inhibi\u010dn\u00ed konstanty) a hodnoty <span class=\"math-inline\" data-math=\"mathbf{EC_{50}}\">EC_50<\/span>-(funk\u010dn\u00ed \u00fa\u010dinnost) u r\u016fzn\u00fdch podtyp\u016f receptor\u016f.<\/li>\n<\/ul>\n<h2>Po\u017eadavky na zaji\u0161t\u011bn\u00ed analytick\u00e9 kvality a laborato\u0159e<\/h2>\n<p>Integrita v\u00fdzkumu vy\u017eaduje maxim\u00e1ln\u00ed \u010distotu a \u00faplnou dokumentaci pou\u017eit\u00e9ho materi\u00e1lu, jeho\u017e kvalita je zaru\u010dena modern\u00edmi analytick\u00fdmi metodami.<\/p>\n<h3>Normy kvality a dokumentace<\/h3>\n<p>V\u00fdzkumn\u00fd materi\u00e1l mus\u00ed m\u00edt chemickou \u010distotu<span class=\"math-inline\" data-math=\"mathbf{ge 98%}\"> 98%$<\/span> maj\u00ed. Toho se dos\u00e1hne <b>Anal\u00fdza HPLC<\/b> potvrzeno.<\/p>\n<ul>\n<li><b>Analytick\u00e1 dokumentace:<\/b> Ka\u017ed\u00e1 \u0161ar\u017ee mus\u00ed b\u00fdt ozna\u010dena <b>\u00fapln\u00e9 certifik\u00e1ty anal\u00fdzy (CoA)<\/b> kter\u00e9 prokazuj\u00ed \u010distotu a identitu (HPLC, GC\/MS).<\/li>\n<li><b>D\u016fslednost:<\/b> <b>Konzistentn\u00ed konzistence \u0161ar\u017e\u00ed<\/b> je z\u00e1sadn\u00ed pro zaji\u0161t\u011bn\u00ed reprodukovatelnosti s\u00e9ri\u00ed test\u016f.<\/li>\n<\/ul>\n<h3>Skladovac\u00ed a bezpe\u010dnostn\u00ed protokoly<\/h3>\n<p>Vzhledem k molekul\u00e1rn\u00ed citlivosti a vysok\u00e9 biologick\u00e9 aktivit\u011b je t\u0159eba dodr\u017eovat p\u0159\u00edsn\u00e9 bezpe\u010dnostn\u00ed protokoly:<\/p>\n<ul>\n<li><b>Skladov\u00e1n\u00ed:<\/b> Materi\u00e1l vy\u017eaduje <b>Bezpe\u010dn\u00e9 skladov\u00e1n\u00ed<\/b> v oblasti s kontrolovan\u00fdm p\u0159\u00edstupem. M\u011bla by <b>Chr\u00e1n\u011bno p\u0159ed sv\u011btlem<\/b>, <b>cool<\/b> (nejl\u00e9pe v mraz\u00e1ku, <span class=\"math-inline\" data-math=\"mathbf{-20^circ C}\">-20 C<\/span>\u00a0a <b>such\u00e9<\/b> b\u00fdt ulo\u017eeny.<\/li>\n<li><b>Osobn\u00ed ochrann\u00e9 prost\u0159edky:<\/b> Pr\u00e1ce mus\u00ed b\u00fdt prov\u00e1d\u011bny v <b>V souladu s GLP<\/b> z\u0159\u00edzen\u00ed. <b>Laboratorn\u00ed pl\u00e1\u0161\u0165, rukavice a ochrann\u00e9 br\u00fdle<\/b> jsou povinn\u00e9.<\/li>\n<li><b>V\u011btr\u00e1n\u00ed:<\/b> S pr\u00e1\u0161kem se mus\u00ed manipulovat pod <b>Chemick\u00e1 digesto\u0159<\/b> se uskute\u010dn\u00ed.<\/li>\n<\/ul>\n<h2>Regula\u010dn\u00ed r\u00e1mec a etick\u00e1 odpov\u011bdnost<\/h2>\n<p>Z\u00e1konn\u00e9 a regula\u010dn\u00ed po\u017eadavky na 25I-NBMD jsou velmi slo\u017eit\u00e9 a vy\u017eaduj\u00ed p\u0159\u00edsn\u00e9 dodr\u017eov\u00e1n\u00ed ze strany v\u00fdzkumn\u00fdch instituc\u00ed.<\/p>\n<h3>Pr\u00e1vn\u00ed status (v z\u00e1vislosti na jurisdikci)<\/h3>\n<p>Pr\u00e1vn\u00ed status 25I-NBMD se v mezin\u00e1rodn\u00edm m\u011b\u0159\u00edtku zna\u010dn\u011b li\u0161\u00ed:<\/p>\n<ul>\n<li>V mnoha regionech spad\u00e1 pod <b>Z\u00e1kony pro psychotropn\u00ed l\u00e1tky<\/b> nebo <b>Analogov\u00e9 ovl\u00e1d\u00e1n\u00ed<\/b> (nap\u0159. NpSG).<\/li>\n<li><b>Povinnost:<\/b> V\u00fdzkumn\u00e9 instituce mus\u00ed <b>m\u00edstn\u00ed p\u0159edpisy p\u0159ed n\u00e1kupem<\/b> zkontrolovat. Odpov\u011bdnost za dodr\u017eov\u00e1n\u00ed z\u00e1kona nese v\u00fdhradn\u011b kupuj\u00edc\u00ed.<\/li>\n<\/ul>\n<h3>Po\u017eadavky na kontrolu akvizice a objedn\u00e1v\u00e1n\u00ed<\/h3>\n<p>Z\u00edsk\u00e1n\u00ed 25I-NBMD je p\u0159\u00edsn\u011b omezeno na dokumentovan\u00fd v\u011bdeck\u00fd v\u00fdzkum.<\/p>\n<ul>\n<li><b>Certifik\u00e1t Institutu:<\/b> Dokumentace v\u00fdzkumn\u00e9 instituce nebo laborato\u0159e je povinn\u00e1.<\/li>\n<li><b>Ur\u010den\u00e9 pou\u017eit\u00ed:<\/b> Je t\u0159eba p\u0159edlo\u017eit v\u011bdeck\u00fd popis v\u00fdzkumn\u00e9ho projektu.<\/li>\n<\/ul>\n<h2>Z\u00e1v\u011br<\/h2>\n<p>25I-NBMD slou\u017e\u00ed jako z\u00e1kladn\u00ed modelov\u00fd syst\u00e9m v neurofarmakologii pro de\u0161ifrov\u00e1n\u00ed mechanism\u016f \u00fa\u010dinku <span class=\"math-inline\" data-math=\"mathbf{5-HT_{2A}}\">5-HT_2A<\/span>-receptor. Laborato\u0159e a v\u011bdeck\u00e9 instituce mohou t\u011b\u017eit z testovan\u00e9 kvality a \u0161irok\u00e9 nab\u00eddky produkt\u016f. N\u00e1kup mus\u00ed b\u00fdt organizov\u00e1n profesion\u00e1ln\u011b a bezpe\u010dn\u011b, p\u0159i\u010dem\u017e <b>Nejvy\u0161\u0161\u00ed priorita<\/b> v\u017edy na <b>Dodr\u017eov\u00e1n\u00ed v\u0161ech z\u00e1kon\u016f a bezpe\u010dnostn\u00edch protokol\u016f<\/b> l\u017ei.<\/p>","protected":false},"excerpt":{"rendered":"<p style=\"text-align: center;\">25I-NBMD<\/p>\n<p>25I-NBMD je syntetick\u00e1 chemick\u00e1 l\u00e1tka pro v\u011bdeck\u00fd v\u00fdzkum. Tento produkt se vyzna\u010duje vysokou \u010distotou a stabilitou, tak\u017ee je ide\u00e1ln\u00ed pro farmakologick\u00e9 studie a anal\u00fdzu receptor\u016f. Ka\u017ed\u00e1 \u0161ar\u017ee je d\u016fkladn\u011b testov\u00e1na, aby byly zaji\u0161t\u011bny konzistentn\u00ed a spolehliv\u00e9 v\u00fdsledky. Ur\u010deno pouze pro laboratorn\u00ed pou\u017eit\u00ed a v\u00fdzkumn\u00e9 projekty.<\/p>","protected":false},"featured_media":6763,"comment_status":"open","ping_status":"closed","template":"","meta":{"_joinchat":[]},"product_brand":[],"product_cat":[1795],"product_tag":[1889,1896,1890,1893,1895,1892,1891,188,1814,1894],"class_list":{"0":"post-6735","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-2c-serie","7":"product_tag-25i-nbmd","8":"product_tag-25i-nbmd-chemikalien","9":"product_tag-25i-nbmd-kaufen","10":"product_tag-25i-nbmd-kristalle","11":"product_tag-25i-nbmd-online","12":"product_tag-25i-nbmd-pulver","13":"product_tag-25i-nbmd-zum-verkauf","14":"product_tag-forschungschemikalien","15":"product_tag-forschungsstoffe-kaufen","16":"product_tag-synthetische-halluzinogene","18":"first","19":"instock","20":"shipping-taxable","21":"purchasable","22":"product-type-variable"},"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.5 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>25I-NBMD online kaufen \u2013 25I-NBMD zu verkaufen<\/title>\n<meta name=\"description\" content=\"In unserem Chemgramx-Onlineshop haben wir 25i-nbmd zu verkaufen. 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