Description
3-CEC hydrochloride (3-chloroethcathinone) is a Premium Analytical Reference Standard from the chemically important class of substituted Cathinones. The Chlorine substitution in the meta-position (3-) of the phenyl ring gives this molecule a specific chemical signature that makes it a indispensable tool in the forensic toxicology and the chemical analysis from new psychoactive substances (NPS) makes. 3-CEC is a key reagent for laboratories specializing in research into the Structure-activity relationships (SAR) chlorinated cathinones and the Validation of detection methods concentrate.
This high-quality Research Chemical Standard is used exclusively for controlled, scientific purposes on qualified experts and Accredited research institutions distributed. We guarantee a analytically confirmed purity of 98% of the hydrochloride salt, which is the absolute basis for precise, traceable and reproducible Measurement results in the Mass spectrometry and Chromatography forms. For laboratories that have a 3-CEC reference standard, Chloroethcathinone control material or analytical reagents for drug analysis we offer the highest quality and compliance security.
Analytical excellence: chemical specifications and quality assurance at the highest level
Molecular identity and guaranteed purity are the main requirements for any forensic standard. The exact characterization of the 3-CEC structure is crucial for the differentiation of isomers (e.g. 4-CEC) and homologues.
Detailed chemical identity and physical properties
3-CEC belongs to the family of Cathinones, which are structurally related to amphetamines, but are characterized by a beta-keto group. The Chlorine substitution in meta-position is the analytical marker of this molecule.
- Chemical class: Substituted cathinones (ethcathinone derivatives).
- Nomenclature: 3-Chloroethcathinone (as hydrochloride salt).
- Chemical formula (base): {C}{11}{H}{14}{ClNO}
- Molar mass: approx 211.69 {g/mol} (base), decisive for the calibration.
- Formulation: Is available as a stable Hydrochloride salt which results in an increased Durability and excellent Solubility in polar solvents (methanol, acetonitrile) for LC-MS/MS-assays are guaranteed.
- Aggregate state: High purity, crystalline powder, optimized for precise gravimetric weighing according to ISO 17025 regulations.
Guaranteed purity through multi-analytical verification and documentation
Our commitment to the purity of 98% is ensured by redundant analytical methods that meet the requirements for GLP and ISO 17025 exceed.
- Primary purity confirmation (quantification): The purity is primarily determined by means of HPLC (High-Performance Liquid Chromatography) the gold standard for the detection of all non-volatile impurities.
- Secondary molecular identification (qualification): The identity is confirmed by at least two independent methods: Gas chromatography-mass spectrometry (GC/MS) and Liquid chromatography tandemMass spectrometry (LC-MS/MS). These methods provide the characteristic fragment ions and spectral signatures, which are essential for the creation of forensic databases.
- Comprehensive certificate of analysis (CoA): Each batch contains a detailed CoA, spectral data, the purity evaluation and the Traceability of the synthesis batch.
- Batch consistency: Thanks to standardized production and cleaning processes, we guarantee a minimum of waste. Batch variability, which is responsible for the Long-term validation of methods over the years is crucial.
Extended areas of application in forensics, toxicology and pharmacology
3-CEC hydrochloride is a critical control molecule for understanding the toxicology of chlorinated stimulants and developing accurate detection methods.
Forensic toxicology, calibration and quality control
The standard is essential for laboratories that analyze samples in critical cases (e.g. traffic toxicology, post-mortem analyses).
- Method validation: The standard is used for Validation from LC-MS/MS and GC-MS Methods for safe Identification and Quantification of cathinones in biological samples. The exact determination of Retention times and MS fragmentation patterns is essential here.
- Calibration: The high-purity material is used to create precise, linear Calibration curves which is the basis for the accurate determination of concentrations in the low nanogram range in forensic matrices.
- Quality control (QC): 3-CEC serves as Reference point for the daily tuning and Performance check sensitive mass spectrometers and as a positive control standard in routine measurements.
Pharmacological and metabolic research
The research uses 3-CEC to investigate the effects of chlorine substitution on the pharmacological profile and metabolism.
- Neurotransmitter studies: Molecular research investigates the Affinity and Potency of the molecule Monoamine transporters (dopamine, noradrenaline, serotonin). These data are essential for predicting the toxicological risk and modeling the in vitro Activity.
- Metabolism identification: Through comprehensive In vitro-Studies all primary and secondary Metabolites of 3-CEC were identified and their structure confirmed. Precise knowledge of these metabolite profiles is essential for forensic laboratories in order to be able to detect the substance even after its degradation and thus extend detection times.
Legal framework and laboratory compliance
The acquisition and handling of this controlled research chemicals are subject to the strictest regulations and are reserved exclusively for scientific research.
Regulatory compliance
As 3-CEC is recognized in many jurisdictions as a controlled substance (e.g. in Germany under the NpSG), distribution is highly regulated.
- Exclusively research: Sales are strictly limited to the Analysis and research in authorized scientific institutions restricted. Any misuse or unauthorized use is not permitted.
- Buyer obligation: The buyer assumes full responsibility for compliance with all local and international laws regarding the import, possession and use of controlled chemicals.
Safety protocols for laboratory users
Strict compliance with the Material Safety Data Sheet (MSDS) is mandatory.
- PSA: Lab coat, safety goggles and chemical resistant Gloves are mandatory. Respiratory masks (FFP3) are strongly recommended when handling powder.
- Working environment: Powder handling must be carried out under certified fume cupboard systems take place.
- Storage: Cool (2-8 °C), dry and protected from light be stored. In addition, storage must be strictly Stock book be documented.
Acquisition of the 3-CEC reference standard - your partner for analytical excellence
We offer 3-CEC hydrochloride in analytically relevant quantities: 100 mg (reference sample), 500 mg and 1 g.
Mandatory order requirements:
- Proof of the Authorization of the research institution.
- Written confirmation that the substance exclusively for analytical reference purposes (calibration, validation, QC) is used.
- Recognition of the Limitations of liability and the MSDS.
For secure, legally compliant and fast ordering of your 3-CEC reference standards to guarantee the Validity of your analytical methods, please contact us directly.






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